Rituo (Re2O) in Gangnam: Effects and Mechanism of an hADM Skin Booster for Dermal Restoration

If your skin seems thinner than before and fine lines or reduced firmness are becoming noticeable, simple moisturizing care alone may feel insufficient.

One option worth looking into at this point is Rituo (Re2O) in Gangnam.

Rituo (Re2O) is an ECM-based skin booster in which acellular dermal matrix (hADM, human Acellular Dermal Matrix) derived from human skin is processed into fine particles and injected into the dermis.

While some existing skin boosters focus on stimulating skin cells to induce new collagen production, Rituo takes a different approach by directly supplementing the extracellular matrix (ECM) components that make up the skin.

It is an option to consider especially if you are concerned about reduced firmness, thinning skin, fine lines or skin texture.

What is Rituo (Re2O)?

Rituo (Re2O) is a treatment in which acellular dermal matrix (hADM, human Acellular Dermal Matrix) derived from human skin is refined into fine particles and injected into the dermis.

hADM is a material made from donated human tissue by removing the cells and fat components that can trigger an immune reaction, leaving only the extracellular matrix (ECM) structure, such as collagen, elastin, hyaluronic acid and GAGs.

Because it is a human-derived material rather than an animal-derived one, it is characterized by high biocompatibility.

What happens inside the skin?

Skin aging and changes in the ECM

As skin aging progresses, the synthesis of collagen and elastin in the dermis decreases, ECM density drops and firmness declines.

Rituo takes the approach of directly supplementing this lost ECM structure from the outside, and is described as having a shorter response time than conventional methods that wait for collagen to be newly synthesized.

hADM raw material is processed in line with the standards of the American Association of Tissue Banks (AATB) and Korea's MFDS human-tissue management system.

What are the treatment steps?

Consultation and treatment design

At the consultation, we analyze skin thickness, firmness and the degree of volume loss to plan the dose and areas.

Anesthesia and dermal injection

Numbing cream is then applied for 20-30 minutes, followed by multi-layer, evenly dispersed injection into the dermis with a fine needle, which takes about 20-30 minutes.

Changes after treatment and doses

Swelling or bruising may appear right after treatment but usually settles within a few days, and many cases report noticing changes in skin density and texture from around 2-4 weeks. Results vary between individuals.

Doses are usually divided into 5 cc, 6 cc and so on, and can be extended from the whole face to the neck and décolleté.

Needle thickness and injection pattern are often designed differently depending on the area, any history of nodules and prior skin booster experience, and even, dispersed injection is regarded as an important factor in reducing nodule formation.

The interval between sessions depends on each person's skin condition, but there are reports that repeating it about 3 times extends the duration to a year or more.

How can you find a trustworthy medical team?

Dr. Hyoseung Jang, Medical Director of Gangnam Pieobom Clinic

Dr. Hyoseung Jang, Director of Gangnam Pieobom Clinic, serves as President of the Korean Association of Clinical Aesthetic Medicine and of the Korean Society of Aesthetic Physicians, and has led regular academic conferences attended by about 1,200 aesthetic-medicine specialists in Korea.

With more than 15 years of treatment experience, the doctor serves as an official Key Doctor for several filler, thread lifting and skin booster brands, and continues to lecture fellow physicians and carry out academic research.

This academic activity and clinical experience translate into an understanding of material characteristics and the ability to design injections for each area.

How does Rituo differ from other skin boosters?

Rituo and other skin boosters differ in the raw materials they use and in their approach. Comparing their characteristics gives the following.

Which skin concerns may suit Rituo better?

You may consider it if you have these skin concerns

However, the appropriate dose and whether to combine other treatments can vary with each person's skin condition and treatment history, so a prior consultation is needed.

What should you check before considering Rituo?

Four things to check before treatment

If you would like a Rituo consultation, you can check available appointment times on the Gangnam Pieobom Clinic Naver booking guide.

If you are considering Rituo

Rather than simply filling the skin with moisture, Rituo is a treatment that takes a different approach from existing skin boosters in that it directly supplements the skin's ECM structure using human-derived hADM.

It may be considered if your skin is thinning, firmness is declining, or you are concerned about both fine lines and skin texture, but even the same treatment can give different results depending on skin condition, injected amount and technique.

It is therefore best to check carefully the product's raw material and authenticity, the doctor's experience with dermal injection, the dose and cost for each area and the post-treatment care system, and then decide through a consultation whether it suits you.

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